As demonstrated in this figure, leads V1 and V2 are in closest proximity to the anterior cardiac chambers and are most likely to demonstrate local electrical events. Leads V3 through V6 become progressively further distanced from the heart itself. Leads V3 and V4 are located approximately over the apex of the heart and leads V5 and V6, which are more or less in closer proximity to the left ventricular lateral wall, are least likely to demonstrate local electrical events.